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Etedesiran

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Etedesiran is a component of the AOC drug Delpacibart etedesiran (HY-177565), formed by the reaction of an siRNA that induces cleavage of mRNA encoding myotonic dystrophy protein kinase (MTPK or DMPK) with SMCC linker (HY-42360). Etedesiran carries a maleimide group at its terminus, which can react with cysteine or lysine and is used for the synthesis of AOC drugs. Etedesiran is applicable to research related to myotonic dystrophy type 1.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 93.16%
  • Molecular Weight:13699.70
  • Speicherung:

    -20°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Etedesiran Chemical Structure
    Etedesiran Chemical Structure
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609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

Alle Antibody-Oligonucleotide Conjugates (AOCs) Isoform-spezifische Produkte anzeigen

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  • Etedesiran Chemical Structure
    Etedesiran Chemical Structure RNA (Cm-sp-Cm-sp-Cm-Um-Am-Gm-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)C-Um-Gm-Um-Cm-Um-Um-Cm-Gm-sp-Am-sp-Am), 5′-[6-[[[4-[(3-mercapto-2,5-dioxo-1-pyrrolidinyl)methyl]cyclohexyl]carbonyl]amino]hexyl hydrogen phosphate], complex with RNA (Um-sp-(2′-deoxy-2′-fluoro)U-sp-Cm-Gm-Am-(2′-deoxy-2′-fluoro)A-Gm-Am-Cm-Am-Gm-Um-Um-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)A-Gm-Gm-Gm-sp-Um-sp-Um)
    1/16
  • RNA (Cm-sp-Cm-sp-Cm-Um-Am-Gm-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)C-Um-Gm-Um-Cm-Um-Um-Cm-Gm-sp-Am-sp-Am), 5′-[6-[[[4-[(3-mercapto-2,5-dioxo-1-pyrrolidinyl)methyl]cyclohexyl]carbonyl]amino]hexyl hydrogen phosphate], complex with RNA (Um-sp-(2′-deoxy-2′-fluoro)U-sp-Cm-Gm-Am-(2′-deoxy-2′-fluoro)A-Gm-Am-Cm-Am-Gm-Um-Um-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)A-Gm-Gm-Gm-sp-Um-sp-Um)