2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1474S1
    Alexidine-d10
    Alexidine-d10 is the deuterium labeled Alexidine (HY-B1474). Alexidine, a bis-biguanide, exhibits antifungal and antibiofilm activity against a diverse range of fungal pathogens. Alexidine is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1, in mammalian cells and causes mitochondrial apoptosis.
    Alexidine-d<sub>10</sub>
  • HY-157074S
    Tandospirone Acid Metabolite-d6
    Tandospirone Acid Metabolite-d6 is deuterium-labeled Tandospirone Acid Metabolite.
    Tandospirone Acid Metabolite-d<sub>6</sub>
  • HY-B0258S1
    Gemfibrozil-d6-1
    Gemfibrozil-d6-1 (CI-719-d6-1) is the deuterium labeled Gemfibrozil (HY-B0258). Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively.
    Gemfibrozil-d<sub>6</sub>-1
  • HY-B0315S1
    Methylcobalamin-d3
    Methylcobalamin-d3 (Mecobalamin-d3) is the deuterium labeled Methylcobalamin (HY-B0586). Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12.
    Methylcobalamin-d<sub>3</sub>
  • HY-B0391S2
    Naftopidil-d7
    Naftopidil-d7 (KT-611-d7 ) is deuterium labeled Naftopidil. Naftopidil (KT-611) is is a selective alpha1-adrenoceptor antagonist, with Kis of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-, α1b- and α1d-adrenoceptor subtypes, respectively. Naftopidil has antiproliferative effects. Naftopidil can be used for the research of prostate hyperplasia.
    Naftopidil-d<sub>7</sub>
  • HY-N0192S
    Arbutin-d4
    Arbutin-d4 is deuterium labeled Arbutin. Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase in melanocytes, with Kiapp values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties.
    Arbutin-d<sub>4</sub>
  • HY-W011588S
    2-Ethylhexyl 4-(dimethylamino)benzoate-d6
    2-Ethylhexyl 4-(dimethylamino)benzoate-d6 (Photoinitiator-EHA-d6) is deuterium labeled 2-Ethylhexyl 4-(dimethylamino)benzoate.
    2-Ethylhexyl 4-(dimethylamino)benzoate-d<sub>6</sub>
  • HY-W010774S
    Bis(1,2,2,6,6-pentamethylpiperidin-4-yl) decanedioate-d6
    Bis(1,2,2,6,6-pentamethylpiperidin-4-yl) decanedioate-d6 is deuterium labeled Bis(1,2,2,6,6-pentamethylpiperidin-4-yl) decanedioate.
    Bis(1,2,2,6,6-pentamethylpiperidin-4-yl) decanedioate-d<sub>6</sub>
  • HY-50896S3
    Erlotinib-d8
    Erlotinib-d8 (CP-358774-d8) is deuterium labeled Erlotinib. Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib-d<sub>8</sub>
  • HY-W116007S
    Octamethylcyclotetrasiloxane-d12
    Octamethylcyclotetrasiloxane-d12 (Octaphenyl silsesquioxane-d12) is deuterium labeled Octamethylcyclotetrasiloxane.
    Octamethylcyclotetrasiloxane-d<sub>12</sub>
  • HY-110168S
    NS 9283-d4
    NS 9283-d4 is the deuterium labeled NS 9283 (HY-110168). NS 9283 is a positive positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors. NS 9283 can be used in a series of neurological conditions such as attention deficit hyperactivity disorder (ADHD), schizophrenia, Parkinson's disease and Alzheimer's disease.
    NS 9283-d<sub>4</sub>
  • HY-W654081
    Bisphenol P-d16
    Bisphenol P-d16 is deuterium labeled α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene.
    Bisphenol P-d<sub>16</sub>
  • HY-131524S
    Taurocholic acid 3-sulfate-d4 disodium
    Taurocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Taurocholic acid 3-sulfate disodium.
    Taurocholic acid 3-sulfate-d<sub>4</sub> disodium
  • HY-146925S
    15:0 Lyso PC-d5
    15:0 Lyso PC-d5 is deuterium labeled 15:0 Lyso PC (HY-W329357). 15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum of patients with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease.
    15:0 Lyso PC-d<sub>5</sub>
  • HY-W009160S
    Octrizole-d4
    Octrizole-d4 (UV-329-d4) is deuterium labeled Octrizole (HY-W009160). Octrizole (UV-329) is a UV screener/stabilizer. Octrizole can prevent products from yellowing and degradation. Octrizole exhibits significant cytotoxicity to MVLN cells at concentrations higher than 50 μM and has no obvious estrogenic activity.
    Octrizole-d<sub>4</sub>
  • HY-144407S
    N-Acetyl-S-(2-carboxyethyl)-L-cysteine-d3
    N-Acetyl-S-(2-carboxyethyl)-L-cysteine-d3 is the deuterium labeled N-Acetyl-S-(2-carboxyethyl)-L-cysteine.
    N-Acetyl-S-(2-carboxyethyl)-L-cysteine-d<sub>3</sub>
  • HY-W092778S
    4,4′-Dibromo diphenyl ether-13C12
    4,4′-Dibromo diphenyl ether-13C12 is 13C labeled 4,4'-Oxybis(bromobenzene).
    4,4′-Dibromo diphenyl ether-<sup>13</sup>C<sub>12</sub>
  • HY-W010319S
    2-Amino-4-methoxy-6-methyl-1,3,5-triazine-d3
    2-Amino-4-methoxy-6-methyl-1,3,5-triazine-d3 (CGA-150829-d3) is deuterium labeled 2-Amino-4-methoxy-6-methyl-1,3,5-triazine.
    2-Amino-4-methoxy-6-methyl-1,3,5-triazine-d<sub>3</sub>
  • HY-10268S1
    Betrixaban-dsub>4
    Betrixaban-d4 (PRT054021-d4) is deuterium labeled Betrixaban. Betrixaban (PRT054021) is a highly potent, selective, and orally efficacious factor Xa (fXa) inhibitor with an IC50 of 1.5 nM. Betrixaban shows antithrombotic effect.
    Betrixaban-dsub>4</sub>
  • HY-W720219S
    2-Amino-2-methylpropane-1-sulfonic acid-d6
    2-Amino-2-methylpropane-1-sulfonic acid-d6 is deuterium-labeled 2-Amino-2-methylpropane-1-sulfonic acid (HY-W720219).
    2-Amino-2-methylpropane-1-sulfonic acid-d<sub>6</sub>