Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W780275S

Alternariol-9-monomethylether sulfate-d₃ ammonium
Alternariol-9-monomethylether sulfate-d₃ (ammonium) is deuterium labeled Alternariol 9-Methyl Ether 3-Sulfate Ammonium Salt.

HY-B0122SS1

Topiramate-¹³C₆-1
Topiramate-¹³C₆-1 (McN 4853-¹³C₆-1; RWJ 17021-¹³C₆-1) is ¹³C-labeled Topiramate (HY-B0122).

HY-176032S

GPAAGPQGP-Arg(¹³C₆,¹⁵N₄) TFA
GPAAGPQGP-Arg(¹³C₆,¹⁵N₄) TFA is the ¹³C- and ¹⁵N-labeled GPAAGPQGP-Arg TFA.

HY-B0102S

Fluoxetine-d₆
Fluoxetine-d₆ (LY-110140 (free base)-d₆) is deuterium labeled Fluoxetine. Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research.

HY-119521S

Mexiletine-d₃
Mexiletine-d₃ (KOE-1173-d₃) is deuterium labeled Mexiletine. Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC₅₀ : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research.

HY-B1716SA

L-5-Hydroxytryptophan-d₃ hydrate		99.14%
L-5-Hydroxytryptophan-d₃ (L-5-HTP-d₃) hydrate is the deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan-d₃ is the deuterium labeled L-5-Hydroxytryptophan. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia.

HY-W342450S

1,1-Diethoxyoctane-d₁₀
1,1-Diethoxyoctane-d10 is a deuterated labeled 1,1-Diethoxyoctane.

HY-15204S

Tonabersat-d₆
Tonabersat-d₆ (SB-220453-d₆) is deuterium labeled Tonabersat. Tonabersat (SB-220453) is a gap-junction modulator. Tonabersat prevents inflammatory damage in the central nervous system.

HY-10353AS2

Raltegravir-d₄ potassium
Raltegravir-d₄ (potassium) (MK 0518-d₄ (potassium)) is deuterium labeled Raltegravir (potassium). Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection.

HY-144370S

S-(5’-Adenosyl)-L-methionine-d₃ (disulfate)
S-(5’-Adenosyl)-L-methionine-d₃ disulfate is the deuterium labeled S-(5’-Adenosyl)-L-methionine disulfate.

HY-17494S1

Timolol-d₉ maleate
Timolol-d₉ (maleate) is deuterium labeled Timolol. Timolol is a β-blocker available for both topical and systemic administration. Topical Timolol is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension. Timolol can also be used for the research of infantile hemangiomas, hypertension, myocardial infarction, migraine prophylaxis, and atrial fibrillation.Timolol also has cardioprotective effect.

HY-W728368

8-(2-Hydroxybenzamido)octanoic acid-d₄
8-(2-Hydroxybenzamido)octanoic acid-d₄ is the deuterium labeled 8-(2-Hydroxybenzamido)octanoic acid.

HY-W653970

5-Azacytidine-¹⁵N₄
5-Azacytidine-¹⁵N₄ is ¹³C and ¹⁵N labeled 5-Azacytidine. 5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation. 5-Azacytidine is incorporated into DNA to covalently trap DNA methyltransferases and contributes to reverse epigenetic changes. 5-Azacytidine induces cell autophagy.

HY-141933S

3-epi-Calcifediol-d₃
3-Epi-25-Hydroxyvitamin D3-d₃ is the deuterium labeled 3-Epi-25-Hydroxyvitamin D3.

HY-17512AS

Losartan-d₆ hydrochloride
Losartan-d₆ hydrochloride is deuterated labeled Losartan potassium (HY-17512A). Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC₅₀ of 20 nM.

HY-173100S

GIFP(Leu-¹³C₆,¹⁵N)AER TFA
GIFP(Leu-¹³C₆,¹⁵N)AER TFA is the ¹³C- and ¹⁵N-labeled GIFP(Leu)AER TFA.

HY-173099S

GNSP(Ile-¹³C₆,¹⁵N)SQR TFA
GNSP(Ile-¹³C₆,¹⁵N)SQR TFA is the ¹³C- and ¹⁵N-labeled GNSP(Ile)SQR TFA.

HY-166879S

SAR107375E Impurity 14-d₈
SAR107375E Impurity 14-d₈ is deuterium labeled SAR107375E Impurity 148.

HY-118827S

Vedaprofen-d₃
Vedaprofen-d₃ is the deuterium labeled Vedaprofen. Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition . Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC₅₀ of 222 μM.

HY-W746944S

N-[2-(1H-Indol-3-yl)acetyl]-L-phenylalanine methyl ester-d₄
N-[2-(1H-Indol-3-yl)acetyl]-L-phenylalanine methyl ester-d₄ is deuterium labeled N-[2-(1H-Indol-3-yl)acetyl]-L-phenylalanine methyl ester.

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