Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1263)
Related Products (1263)
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mPEG10000-DMG
0 ImagesCat. No.: HY-W1052148BCAS No.: 160743-62-4mPEG10000-DMG is a PEGylated phospholipid containing DMG. mPEG10000-DMG combines the membrane fusion capability of DMG with the stealth properties of PEG, and can be used for applications such as constructing targeted drug delivery systems and liposome preparation.
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DSPE-PEG5000-T7
0 ImagesCat. No.: HY-172724DSPE-PEG5000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG5000-T7 can be used for drug delivery.
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DSG-PEG10000-SH
0 ImagesCat. No.: HY-183055DSynonyms: DSG-PEG10000-ThiolDSE-PEG10000-SH (DSE-PEG10000-Thiol) is a conjugate composed of DSE, a PEG chain, and a terminal thiol group (-SH). The thiol group in DSE-PEG10000-SH exhibits strong chemical reactivity and can participate in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
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DMPE-PEG350 ammonium
0 ImagesCat. No.: HY-155924CAS No.: 474922-82-2Synonyms: 14:0 PEG350 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammoniumDMPE-PEG350 ammonium (14:0 PEG350 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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DPPE-PEG3400-NHS
0 ImagesCat. No.: HY-182833BCAS No.: 355150-30-0DPPE-PEG3400-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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DSG-PEG5000-COOH
0 ImagesCat. No.: HY-183173CDSG-PEG5000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
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DMG-PEG2000-CHO
0 ImagesCat. No.: HY-183398ADMG-PEG2000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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16:0 Cardiolipin
0 ImagesCat. No.: HY-159856CAS No.: 105380-95-8Synonyms: Diphosphatidylglycerol (16:0)
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Lipid 119-23
0 ImagesCat. No.: HY-171019CAS No.: 2953044-98-7Lipid 119-23 is an ionizable cationic lipid which can be utilized in the formation of lipid nanoparticles and the delivery of mRNA. Lipid 119-23 exhibits an enhanced capability to express functional mCre in several categories of immune cells, spanning the liver, spleen and lung.
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DSG-PEG5000-CHO
0 ImagesCat. No.: HY-183171BDSG-PEG5000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG5000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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DSPE-PEG600-NHS
0 ImagesCat. No.: HY-W441012DSPE-PEG600-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG600-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG600-NHS can be used in the study of drug delivery.
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GL67
0 ImagesCat. No.: HY-149037CAS No.: 179075-30-0Synonyms: N4-Spermine cholesteryl carbamateGL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid that serves as a non-viral siRNA delivery vector and a non-viral gene transfer vector. GL67 enhances the encapsulation efficiency of siRNA in liposomal formulations and promotes the cellular uptake of siRNA across cancer cell membranes. GL67 mediates the transduction of plasmid DNA into cells. GL67 can be used in drug delivery-related research.
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DMG-PEG1000-DBCO
0 ImagesCat. No.: HY-183195DMG-PEG1000-DBCO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal dibenzocyclooctylene (DBCO). DMG-PEG1000-DBCO combines the membrane compatibility of phospholipids with the high reactivity of the DBCO group in copper-free click chemistry, making it suitable for research in biomaterial construction and drug delivery.
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Cholesterol-PEG1000-Thiol
0 ImagesCat. No.: HY-W440722Cholesterol-PEG1000-Thiol is a PEGylated lipid that forms micelles in water and can be used to prepare liposomes or nanoparticles as drug delivery systems. The thiol moiety reacts with maleimide to form a stable thioether bond.
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DSPE PEG2k-OH ammonium
0 ImagesCat. No.: HY-N15973CAS No.: 3056014-08-2DSPE PEG2k-OH ammonium is a hydroxyl-terminated PEGylated phospholipid. The hydrophobic tail allows for the encapsulation and aggregation of other hydrophobic drugs, and the hydroxyl terminus is suitable for further reactions. DSPE PEG2k-OH ammonium can be used to prepare liposomes or lipid nanoparticles.
