2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (1005):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W590536
    1,2-PLPC
    1,2-PLPC is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
    1,2-PLPC
  • HY-172474
    DSPE-PEG5000-NGR
    DSPE-PEG5000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG5000-NGR can be used for drug delivery.
    DSPE-PEG5000-NGR
  • HY-W591332
    mPEG2000-DMPE
    mPEG2000-DMPE is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
    mPEG2000-DMPE
  • HY-155887
    DSPE-PEG-Amine, MW 3400 ammonium
    DSPE-PEG-Amine (DSPE-PEG-NH2), MW 3400 ammonium is an amino-functionalized PEGylated phospholipid. It serves not only as a key component for preparing σ receptor-targeted liposomes (such as anisamide-modified lipids) but also as a starting material for synthesizing click chemistry- and tumor-targeted lipids including DSPE-PEG-DBCO (HY-155788) and DSPE-PEG2000-TCO (HY-170704). DSPE-PEG-Amine, MW 3400 ammonium effectively modulates the ζ potential of nanoparticles, enables complexation with nucleic acids or proteins to protect DNA from nuclease degradation, and supports ligand conjugation on the nanoparticle surface. It is used in studies related to DU-145 tumors, breast cancer, and other relevant research.
    DSPE-PEG-Amine, MW 3400 ammonium
  • HY-177827
    Liposomal Vitamin B3
    Liposomal Vitamin B3 is a specialized delivery system that encapsulates vitamin B3 within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of vitamin B3. Vitamin B3 (Nicotinamide) is one of the water-s
    Liposomal Vitamin B3
  • HY-172467
    DSPE-PEG2000-CTT2
    DSPE-PEG2000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG2000-CTT2 can be used for drug delivery.
    DSPE-PEG2000-CTT2
  • HY-172690A
    DSPE-PEG3400-THRPPMWSPVWP
    DSPE-PEG3400-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells.
    DSPE-PEG3400-THRPPMWSPVWP
  • HY-172278A
    DSPE-PEG2000-CGKRK
    DSPE-PEG2000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG2000-CGKRK can be used for drug delivery.
    DSPE-PEG2000-CGKRK
  • HY-172502
    DSPE-PEG1000-Mal-Cys-KAAKNK
    DSPE-PEG1000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG1000-KAA can be used for drug delivery.
    DSPE-PEG1000-Mal-Cys-KAAKNK
  • HY-144023
    16:0-18:1 EPC chloride
    16:0-18:1 EPC chloride is a cationic lipid, which can be used for liposomes applied in drug delivery.
    16:0-18:1 EPC chloride
  • HY-144013D
    18:0 mPEG1000 PE ammonium
    18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
    18:0 mPEG1000 PE ammonium
  • HY-179677B
    DSPE-PEG5000-DT7
    DSPE-PEG5000-Mal-Cys-DT7 is a phospholipid-PEG conjugate. DSPE-PEG5000-Mal-Cys-DT7 utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles.
    DSPE-PEG5000-DT7
  • HY-172274
    DSPE-PEG1000-Mal-Cys-APRPG
    DSPE-PEG1000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG1000-APRPG can be used for drug delivery.
    DSPE-PEG1000-Mal-Cys-APRPG
  • HY-172696A
    DSPE-PEG3400-WYRGRL
    DSPE-PEG3400-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG3400-WYRGRL can be used for drug delivery.
    DSPE-PEG3400-WYRGRL
  • HY-133952
    7-Oxotridecanedioic acid
    7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents.
    7-Oxotridecanedioic acid
  • HY-177204B
    DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW
    DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW can be used for drug delivery.
    DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW
  • HY-W140488
    1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine
    1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine, a phospholipid, showes very promising P-gp inhibitory results at a concentration of 0.3 mM.
    1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine
  • HY-157699
    1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium
    1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium is a membrane-bound signaling molecule with intracellular activity in regulating membrane trafficking and signal transduction. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can be used in the preparation of liposomes to enhance the efficiency of compound delivery. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can also act as a coordinator of the actin cytoskeleton and participate in the regulation of cell morphology and motility.
    1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium
  • HY-128937
    EC1454
    EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy.
    EC1454
  • HY-171113
    CP-LC-1074
    CP-LC-1143 is an ionizable cationic amino lipid efficient delivery of different kinds of RNA (mRNA, cRNA and saRNA).
    CP-LC-1074