Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1265)
Related Products (1265)
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1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol
0 ImagesCat. No.: HY-148601CAS No.: 217939-97-4Synonyms: DSPG1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (DSPG) is an anionic (negatively charged) phospholipid. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is used to prepare lipid microbubbles as ultrasound contrast agents. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol can be used to construct liposomes as vaccine carriers for the treatment of atherosclerosis. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is applicable to the research of drug delivery and diagnostic preparations.
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DOPE-PEG1000-Amine
0 ImagesCat. No.: HY-W440990Synonyms: DOPE-PEG1000-NH2DOPE-PEG1000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG1000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
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DMG-PEG3400-Glucose
0 ImagesCat. No.: HY-183156BDMG-PEG3400-Glucose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal glucose. DMG-PEG3400-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
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DSPE-PEG2000-MG1
0 ImagesCat. No.: HY-182096ADSPE-PEG2000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG2000-KTP can be used for drug delivery.
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DMT7
0 ImagesCat. No.: HY-171114CAS No.: 3080542-12-4DMT7 is an ionizable cationic lipid (pKa = 6.5) that can be used to generate lipid nanoparticles (LNPs) for delivery of mRNA and anticancer drugs in the body.
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DOPE-PEG5000-NHS
0 ImagesCat. No.: HY-203300CDOPE-PEG5000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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DSPE-PEG1000-VHPKQHRGGSKGC
0 ImagesCat. No.: HY-182101DSPE-PEG1000-VHPKQHRGGSKGC is a targeted modified phospholipid-polyethylene glycol conjugate covalently coupled to DSPE, PEG, and the vascular-targeting peptide VHPKQHRGGSKGC. DSPE-PEG1000-VHPKQHRGGSKGC can be used for research on tumor vascular imaging and vascular-targeted drug delivery.
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DSPE-PEG5000-Mannose
0 ImagesCat. No.: HY-168374BCAS No.: 1829524-73-3DSPE-PEG5000-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG5000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.
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DSPE-PEG3400-TAASGVRSMH
0 ImagesCat. No.: HY-172482ADSPE-PEG3400-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3400-TAASGVRSMH can be used for drug delivery.
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DPPE-PEG5000-NH2
0 ImagesCat. No.: HY-W1052523BDPPE-PEG5000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG5000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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DSPE-PEG1000-VIP
0 ImagesCat. No.: HY-172680DSPE-PEG1000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG1000-VIP can be used for drug delivery.
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16:0 MPB PE
0 ImagesCat. No.: HY-W800789CAS No.: 384835-50-116:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.
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DSPE-PEG2000-PTP
0 ImagesCat. No.: HY-172270ADSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors.
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DSPE-PEG2000-COOH
0 ImagesCat. No.: HY-184721CAS No.: 1403812-41-8DSPE-PEG2000-COOH is a conjugate composed of DSPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSPE-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, for targeted modification of liposomes/nanoparticles.
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DSPE-PEG2000-Maleimide free acid
0 ImagesDSPE-PEG2000-Maleimide free acid is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide free acid utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide free acid covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide free acid can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration.
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DSPE-PEG1000-EB1
0 ImagesCat. No.: HY-172725DSPE-PEG1000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG1000-EB1 can be used for drug delivery.
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DSPE-PEG2000-FAP
0 ImagesCat. No.: HY-184436Synonyms: DSPE-PEG2000-DRGETGPACDSPE-PEG-FAP (DSPE-PEG2000-DRGETGPAC) is a functionalized phospholipid molecule composed of three parts: lipid anchor (DSPE), PEG2000, and a fibroblast activation protein (FAP) targeting peptide. DSPE-PEG-FAP can be used in drug delivery-related research.
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18:1 PE MCC
0 ImagesCat. No.: HY-W800787CAS No.: 384847-49-818:1 PE MCC is a reactive phospholipid containing a maleimide group. 18:1 PE MCC forms covalent bonds with thiol-modified chondroitin sulfate (CS) via thiol-maleimide reaction, and anchors CS to the surface of lipid membranes. 18:1 PE MCC is applicable to glycocalyx model construction and lipid membrane biophysics research.
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LCA-H10
0 ImagesCat. No.: HY-P11614LCA-H10 is a lithocholic acid-histidine decapeptide conjugate, a biocompatible lipid nanoparticle (LNP) additive that reduces ionizable lipid proportions, functions as an endosomal escape inducer, and enhances siRNA encapsulation. LCA-H10 increases hepatic accumulation of LNPs in mice after intravenous injection when incorporated into LiLNP-LH and reduces proinflammatory cytokines (IL-6, TNF, IL-1β) in mouse serum. LCA-H10 can be used for the research of prostate cancer.
