1829524-73-3
Chemical Structure
DSPE-PEG2000-Mannose
- CAS No.: 1829524-73-3
- Formula:N/A
- Molecular Weight:2000 (Average)
SMILES: CCCCCCCCCCCCCCCCCC(O[C@@H](COP(OCCNC(OCCOCCNC(NC1=CC=C(O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C=C1)=S)=O)(O)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O.[n]
Biological Activity: DSPE-PEG 2000-Mannose is a mannose-containing lipid. DSPE-PEG 2000-Mannose is used to prepare mannose-conjugated Liposome (Man-lipo) for siRNA delivery. Mannose-modified liposomes encapsulating IDO siRNA (Man-lipo-siIDO) preferentially knock down IDO expression in the draining lymph nodes and spleens of melanoma-bearing mice. Man-lipo-siIDO delays the onset time of melanoma and reduces tumor volume[1].
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DSPE-PEG2000-Mannose | 90.0% | DSPE-PEG 2000-Mannose is a mannose-containing lipid. DSPE-PEG 2000-Mannose is used to prepare mannose-conjugated Liposome (Man-lipo) for siRNA delivery. Mannose-modified liposomes encapsulating IDO siRNA (Man-lipo-siIDO) preferentially knock down IDO expression in the draining lymph nodes and spleens of melanoma-bearing mice. Man-lipo-siIDO delays the onset time of melanoma and reduces tumor volume. | ||||||||||||||||||||
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DSPE-PEG5000-Mannose | DSPE-PEG5000-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG5000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery. | |||||||||||||||||||||
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DSPE-PEG10000-Mannose | DSPE-PEG10000-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG10000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery. | |||||||||||||||||||||
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DSPE-PEG1000-Mannose | DSPE-PEG1000-mannose is an amphiphilic molecule that can be used to synthesize lipid nanoparticles. | |||||||||||||||||||||
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DSPE-PEG3400-Mannose | DSPE-PEG3400-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG3400-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery. | |||||||||||||||||||||
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