2. Epigenetics
  3. Histone Acetyltransferase
  4. Acetylethylcholine mustard hydrochloride

Acetylethylcholine mustard hydrochloride  (Synonyms: Acetyl-AF64)

Cat. No.: HY-124892A
COA
SDS
Handling Instructions Technical Support

Acetylethylcholine mustard hydrochloride (Acetyl-AF64) is an inhibitor of choline acetyl-transferase that reduces the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC50) of 1.22 mM. Acetylethylcholine mustard hydrochloride is an irreversible ligand for the high affinity choline transport system. Acetylethylcholine mustard hydrochloride is also a cholinotoxin. Acetylethylcholine mustard hydrochloride is a precursor for ethylcholine mustard aziridinium ion.

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Acetylethylcholine mustard hydrochloride

Acetylethylcholine mustard hydrochloride Chemical Structure

CAS No. : 103994-00-9

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Acetylethylcholine mustard hydrochloride Related Antibodies

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Description

Acetylethylcholine mustard hydrochloride (Acetyl-AF64) is an inhibitor of choline acetyl-transferase that reduces the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC50) of 1.22 mM. Acetylethylcholine mustard hydrochloride is an irreversible ligand for the high affinity choline transport system. Acetylethylcholine mustard hydrochloride is also a cholinotoxin. Acetylethylcholine mustard hydrochloride is a precursor for ethylcholine mustard aziridinium ion[1][2].

Molecular Weight

230.13

Formula

C8H17Cl2NO2
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

CCN(CCOC(C)=O)CCCl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (217.27 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3454 mL 21.7269 mL 43.4537 mL
5 mM 0.8691 mL 4.3454 mL 8.6907 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.61%

SDS (645 KB)

COA (244 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.3454 mL 21.7268 mL 43.4537 mL 108.6342 mL
5 mM 0.8691 mL 4.3454 mL 8.6907 mL 21.7268 mL
10 mM 0.4345 mL 2.1727 mL 4.3454 mL 10.8634 mL
15 mM 0.2897 mL 1.4485 mL 2.8969 mL 7.2423 mL
20 mM 0.2173 mL 1.0863 mL 2.1727 mL 5.4317 mL
25 mM 0.1738 mL 0.8691 mL 1.7381 mL 4.3454 mL
30 mM 0.1448 mL 0.7242 mL 1.4485 mL 3.6211 mL
40 mM 0.1086 mL 0.5432 mL 1.0863 mL 2.7159 mL
50 mM 0.0869 mL 0.4345 mL 0.8691 mL 2.1727 mL
60 mM 0.0724 mL 0.3621 mL 0.7242 mL 1.8106 mL
80 mM 0.0543 mL 0.2716 mL 0.5432 mL 1.3579 mL
100 mM 0.0435 mL 0.2173 mL 0.4345 mL 1.0863 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Acetylethylcholine mustard hydrochloride Related Classifications

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Keywords:

Acetylethylcholine mustard103994-00-9Acetyl-AF64Histone AcetyltransferaseHATsHATcholine acetyl-transferaseAchcholine transport systemcholinotoxinInhibitorinhibitorinhibit

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