CBX8 Antibody (YA9715)

(Synonyms: Cbx8, CBX8_HUMAN, Chromobox Homolog 8 (Drosophila Pc Class), Chromobox Homolog 8 (Pc Class Homolog, Drosophila), Chromobox Homolog 8, Chromobox protein homolog 8, hPc3, Pc Class 3 Homolog (Drosophila), Pc Class 3 Homolog, Pc3)

CBX8 Antibody (YA9715) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to CBX8.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF, FC, IP

  • Reactivity :

    Human, Mouse, Rat, Monkey

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:1000 1:100 1-2μg/sample

Product Details

Description

CBX8 Antibody (YA9715) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to CBX8.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat, Monkey
  • Calculated Molecular Weight Predicted band size: 43 kDa;
Immunogen

Recombinant protein of human Cbx8 (aa 51-389).

Sensitivity

Endogenous

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CBX8 is a Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility

  • Subcellular Localization

    Nucleus

  • Isoforms & Post-Translational Modification

    CBX8 has an amino acid length of 389, molecular weight is 43396 Da.

  • Subunit

    Component of a PRC1-like complex.

  • SwissProt ID

    Q9HC52

  • Synonyms

    Cbx8, CBX8_HUMAN, Chromobox Homolog 8 (Drosophila Pc Class), Chromobox Homolog 8 (Pc Class Homolog, Drosophila), Chromobox Homolog 8, Chromobox protein homolog 8, hPc3, Pc Class 3 Homolog (Drosophila), Pc Class 3 Homolog, Pc3

CBX8 Antibody (YA9715) Related Classifications

MOQ
Minimum order quantity
100 mg

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