CBX8 Antibody (YA9715)
(Synonyms: Cbx8, CBX8_HUMAN, Chromobox Homolog 8 (Drosophila Pc Class), Chromobox Homolog 8 (Pc Class Homolog, Drosophila), Chromobox Homolog 8, Chromobox protein homolog 8, hPc3, Pc Class 3 Homolog (Drosophila), Pc Class 3 Homolog, Pc3)CBX8 Antibody (YA9715) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to CBX8.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, FC, IP
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Reactivity :
Human, Mouse, Rat, Monkey
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
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|---|---|---|---|
| Dilution Ratio | 1:1000 | 1:100 | 1-2μg/sample |
Product Details
CBX8 Antibody (YA9715) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to CBX8.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat, Monkey
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Calculated Molecular Weight Predicted band size: 43 kDa;
Recombinant protein of human Cbx8 (aa 51-389).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CBX8 is a Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
CBX8 has an amino acid length of 389, molecular weight is 43396 Da.
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Subunit
Component of a PRC1-like complex.
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SwissProt ID
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Synonyms
Cbx8, CBX8_HUMAN, Chromobox Homolog 8 (Drosophila Pc Class), Chromobox Homolog 8 (Pc Class Homolog, Drosophila), Chromobox Homolog 8, Chromobox protein homolog 8, hPc3, Pc Class 3 Homolog (Drosophila), Pc Class 3 Homolog, Pc3
Documentation