L1CAM Antibody (YA1370)

(Synonyms: L1CAM; CAML1; MIC5; Neural cell adhesion molecule L1; N-CAM-L1; NCAM-L1; CD antigen CD171)

L1CAM Antibody (YA1370) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to L1CAM.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Conjugation:
    Non-conjugated

Applications

Application
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:50-1:100 1:10000

Product Details

Descripciòn

L1CAM Antibody (YA1370) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to L1CAM.

  • Host Rabbit
  • Clonality Recombinant, Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 140 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 140 kDa
Species Reactivity Database

Entrez Gene: 3897 Human

SwissProt: P32004 Human

Immunogen

Recombinant human CD171 protein

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Envío

    Shipping with blue ice.

Background

  • Function

    Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity

  • Subcellular Localization

    Cell membrane; Single-pass type I membrane protein; Cell projection, growth cone; Cell projection, axon; Cell projection, dendrite

  • Isoforms & Post-Translational Modification

    P32004 has 3 isomers: P32004-1: 140003 Da (predicted); P32004-2: 139517 Da (predicted); P32004-3: 138908 Da (predicted).

  • Subunit

    Interacts with SHTN1; the interaction occurs in axonal growth cones (By similarity). Interacts with isoform 2 of BSG (By similarity)

  • SwissProt ID

    P32004

  • Gene ID
  • Synonyms

    L1CAM; CAML1; MIC5; Neural cell adhesion molecule L1; N-CAM-L1; NCAM-L1; CD antigen CD171

  • Research Field

    Signal Transduction

L1CAM Antibody (YA1370) Related Classifications