HSD17B2 Antibody (YA8072)
(Synonyms: EDH17B2; HSD17; SDR9C2)HSD17B2 Antibody (YA8072) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HSD17B2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
FC
FC: Flow Cytometry
|
|---|---|
| Dilution Ratio | 1:100 |
Product Details
HSD17B2 Antibody (YA8072) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HSD17B2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 42.6 kDa
Full length human recombinant protein of human HSD17B2 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
HSD17B2 catalyzes the NAD-dependent oxidation of the highly active 17beta-hydroxysteroids, such as estradiol (E2), testosterone (T), and dihydrotestosterone (DHT), to their less active forms and thus regulates the biological potency of these steroids. Oxidizes estradiol to estrone, testosterone to androstenedione, and dihydrotestosterone to 5alpha-androstan-3,17-dione. Also has 20-alpha-HSD activity
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Subcellular Localization
Endoplasmic reticulum membrane
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Expression
Tissue_Specificity: Expressed in placenta -
Isoforms & Post-Translational Modification
P37059: 387 amino acids, molecular weight 42785 Da.
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Subunit
Homodimer
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SwissProt ID
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Synonyms
EDH17B2; HSD17; SDR9C2
Documentation
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