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  4. LMCD1 Antibody (YA7960)

LMCD1 Antibody (YA7960) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LMCD1.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • Beschreibung

Beschreibung

LMCD1 Antibody (YA7960) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LMCD1.

Host

Mouse

Clonality

Monoclonal

Molekulargewicht

Predicted band size: 40.7 kDa

Species Reactivity
Human, Mouse, Rat
SwissProt ID
Immunogen

Full length human recombinant protein of human LMCD1 produced in HEK293T cell.

Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:2000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:150-500
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:100-250
FC
FC: Flow Cytometry
1:100
Sensitivity Endogenous Reinheit Affinity purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG1  
Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Versand

Shipping with blue ice.

Background
Function:Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway
Subcellular Localization:Cytoplasm,Nucleus
Expression:
Tissue_Specificity: Expressed in the heart (at protein level). Expressed in many tissues with highest abundance in skeletal muscle
Isoforms & Post-Translational Modification:Q9NZU5 has two isomers: Q9NZU5-1: 40833 Da (predicted); Q9NZU5-2: 32882 Da (predicted).
Subunit:Interacts with GATA1 and GATA4 (By similarity)
Synonyms
dyxin; LIM and cysteine-rich domains 1
Dokumentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Produktname:
LMCD1 Antibody (YA7960)
Art. -Nr.:
HY-P88276
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