PDGFD Antibody (YA7882)

Cat. No.: HY-P88198: Data Sheet User Guide for Antibodies
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PDGFD Antibody (YA7882) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PDGFD.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

PDGFD Antibody (YA7882) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PDGFD.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 40.2 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9GZP0

Immunogen

Human recombinant protein fragment corresponding to amino acids 19-247 of human PDGFD produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity)

Subcellular Localization：Secreted

Expression：
Tissue_Specificity: Expressed at high levels in the heart, pancreas, adrenal gland and ovary and at low levels in placenta, liver, kidney, prostate, testis, small intestine, spleen and colon. In the kidney, expressed by the visceral epithelial cells of the glomeruli. A widespread expression is also seen in the medial smooth muscle cells of arteries and arterioles, as well as in smooth muscle cells of vasa rectae in the medullary area. Expressed in the adventitial connective tissue surrounding the suprarenal artery. In chronic obstructive nephropathy, a persistent expression is seen in glomerular visceral epithelial cells and vascular smooth muscle cells, as well as de novo expression by periglomerular interstitial cells and by some neointimal cells of atherosclerotic vessels. Expression in normal prostate is seen preferentially in the mesenchyme of the gland while expression is increased and more profuse in prostate carcinoma. Expressed in many ovarian, lung, renal and brain cancer-derived cell lines

Isoforms & Post-Translational Modification：Q9GZP0 has two isomers: Q9GZP0-1: 42848 Da (predicted); Q9GZP0-2: 42167 Da (predicted).
Activated by proteolytic cleavage

Subunit：Homodimer; disulfide-linked

Synonyms

IEGF; MSTP036; SCDGF-B; SCDGFB

Documentation

User Guide for Antibodies (1077 KB)