TRIM9 Antibody (YA8420)
(Synonyms: RNF91; SPRING)TRIM9 Antibody (YA8420) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TRIM9.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
TRIM9 Antibody (YA8420) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TRIM9.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 61.2 kDa
Human recombinant protein fragment corresponding to amino acids 284-669 of human TRIM9 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TRIM9 is an E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation
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Subcellular Localization
Cytoplasm,Cell projection, dendrite,Cytoplasmic vesicle, secretory vesicle, synaptic vesicle,Synapse,Cytoplasm, cytoskeleton
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Expression
Tissue_Specificity: Brain. Highly expressed in the cerebral cortex (at protein level). Severely decreased in the affected brain areas in Parkinson disease and dementia with Lewy bodies -
Isoforms & Post-Translational Modification
Q9C026 has three isomers: Q9C026-1: 79177 Da (predicted); Q9C026-4: 89762 Da (predicted); Q9C026-5: 61346 Da (predicted).
Auto-ubiquitinated -
Subunit
Interacts with SNAP25
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SwissProt ID
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Synonyms
RNF91; SPRING
Documentation
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