2-Hydroxybenzimidazole
Based on 1 Customer Validation
2-Hydroxybenzimidazole is an inactive compound targeting CYP1A1 and is mainly used as a control compound in the structure-activity relationship study of benzimidazole derivatives. 2-Hydroxybenzimidazole does not have the ability to induce CYP1A1 expression like its thiol or amino substituted derivatives.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.98%
- CAS. Nr.: 615-16-7
- Formel: C7H6N2O
- Molecular Weight:134.14
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Metabolism/Protease Compound Library
HY-L012
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Anti-Aging Compound Library
HY-L034
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Antioxidant Compound Library
HY-L037
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Oxygen Sensing Compound Library
HY-L045
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Mitochondria-Targeted Compound Library
HY-L089
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Metabolic Enzyme Compound Library
HY-L146
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Radioprotector Library
HY-L178
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
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Drug Fragment Library
HY-L904
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MCE Kinase Hinge Binder Fragment Library
HY-L907
Biologische Aktivität
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CYP1A1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>100 μM
Compound: 7
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Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay
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[PMID: 23243487] |
Chemical Information
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CAS. Nr. 615-16-7
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Appearance Solid
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Molecular Weight 134.14
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Formel C7H6N2O
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Color Off-white to light brown
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SMILES
O=C1NC2=CC=CC=C2N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 50 mg/mL (372.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.4549 mL | 37.2745 mL | 74.5490 mL | 186.3724 mL |
| 5 mM | 1.4910 mL | 7.4549 mL | 14.9098 mL | 37.2745 mL | |
| 10 mM | 0.7455 mL | 3.7274 mL | 7.4549 mL | 18.6372 mL | |
| 15 mM | 0.4970 mL | 2.4850 mL | 4.9699 mL | 12.4248 mL | |
| 20 mM | 0.3727 mL | 1.8637 mL | 3.7274 mL | 9.3186 mL | |
| 25 mM | 0.2982 mL | 1.4910 mL | 2.9820 mL | 7.4549 mL | |
| 30 mM | 0.2485 mL | 1.2425 mL | 2.4850 mL | 6.2124 mL | |
| 40 mM | 0.1864 mL | 0.9319 mL | 1.8637 mL | 4.6593 mL | |
| 50 mM | 0.1491 mL | 0.7455 mL | 1.4910 mL | 3.7274 mL | |
| 60 mM | 0.1242 mL | 0.6212 mL | 1.2425 mL | 3.1062 mL | |
| 80 mM | 0.0932 mL | 0.4659 mL | 0.9319 mL | 2.3297 mL | |
| 100 mM | 0.0745 mL | 0.3727 mL | 0.7455 mL | 1.8637 mL |
2-Hydroxybenzimidazole Related Classifications
HY-W008003 Related Classifications
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