cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Definition:
References:
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[1]. Kam Y J Zhang, et al. A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases. Mol Cell. 2004 Jul 23;15(2):279-86. [Content Brief]
[2]. R X Xu, et al. Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity. Science. 2000 Jun 9;288(5472):1822-5. [Content Brief]
[3]. Robert X Xu, et al. Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram. J Mol Biol. 2004 Mar 19;337(2):355-65. [Content Brief]