Claudin-17

Definition:

Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability.

References:

[1]. Susanne M Krug, et al. Claudin-17 forms tight junction channels with distinct anion selectivity. Cell Mol Life Sci. 2012 Aug;69(16):2765-78. [Content Brief]

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