Endoplasmic reticulum-Golgi intermediate compartment protein 3

Definition:

Possible role in transport between endoplasmic reticulum and Golgi. Positively regulates trafficking of the secretory proteins SERPINA1/alpha1-antitrypsin and HP/haptoglobin.

References:

[1]. Wonjin Yoo, et al. The E3 ubiquitin ligase MARCH2 regulates ERGIC3-dependent trafficking of secretory proteins. J Biol Chem. 2019 Jul 12;294(28):10900-10912. [Content Brief]

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