Interferon regulatory factor 5
Definition:
References:
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[1]. Leonhard X Heinz, et al. TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9. Nature. 2020 May;581(7808):316-322. [Content Brief]
[2]. Xin Yin, et al. MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells. Cell Rep. 2021 Jan 12;34(2):108628. [Content Brief]
[3]. Hui-Chen Chang Foreman, et al. Activation of interferon regulatory factor 5 by site specific phosphorylation. PLoS One. 2012;7(3):e33098. [Content Brief]
[4]. Annett Schoenemeyer, et al. The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling. J Biol Chem. 2005 Apr 29;280(17):17005-12. [Content Brief]
[5]. B J Barnes, et al. Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. J Biol Chem. 2001 Jun 29;276(26):23382-90. [Content Brief]
[6]. Marta Lopez-Pelaez, et al. Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17432-7. [Content Brief]
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