Mitochondrial import receptor subunit TOM34

Definition:

Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state.

References:

[1]. S D Nuttall, et al. hTom34: a novel translocase for the import of proteins into human mitochondria. DNA Cell Biol. 1997 Sep;16(9):1067-74. [Content Brief]

[2]. N Chewawiwat, et al. Characterization of the novel mitochondrial protein import component, Tom34, in mammalian cells. J Biochem. 1999 Apr;125(4):721-7. [Content Brief]

[3]. Abhijit Mukhopadhyay, et al. Tom34 unlike Tom20 does not interact with the leader sequences of mitochondrial precursor proteins. Arch Biochem Biophys. 2002 Apr 1;400(1):97-104. [Content Brief]

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