Shugoshin 1
Definition:
References:
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[1]. Tatsuya Tsukahara, et al. Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation. Nature. 2010 Oct 7;467(7316):719-23. [Content Brief]
[2]. Zhanyun Tang, et al. PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Dev Cell. 2006 May;10(5):575-85. [Content Brief]
[3]. Guosheng Fu, et al. Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis. Cell Res. 2007 Jul;17(7):608-18. [Content Brief]
[4]. Barry E McGuinness, et al. Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. PLoS Biol. 2005 Mar;3(3):e86. [Content Brief]
[5]. Xiaoxing Wang, et al. sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1. Dev Cell. 2008 Mar;14(3):331-41. [Content Brief]
[6]. Zhanyun Tang, et al. Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis. Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):18012-7. [Content Brief]
[7]. Jeroen Pouwels, et al. Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1. Cell Cycle. 2007 Jul 1;6(13):1579-85. [Content Brief]
[8]. Tomoya S Kitajima, et al. Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization. Curr Biol. 2005 Feb 22;15(4):353-9. [Content Brief]