Terminal nucleotidyltransferase 5D
Definition:
Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group.
References:
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[1]. Hua Chen, et al. Structural and Functional Analyses of the FAM46C/Plk4 Complex. Structure. 2020 Aug 4;28(8):910-921.e4. [Content Brief]
[2]. Seweryn Mroczek, et al. The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma. Nat Commun. 2017 Sep 20;8(1):619. [Content Brief]
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