Tetratricopeptide repeat protein 29
Definition:
Axonemal protein which is implicated in axonemal and/or peri-axonemal structures assembly and regulates flagella assembly and beating and therefore sperm motility.
References:
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[1]. Chunyu Liu, et al. Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice. Am J Hum Genet. 2019 Dec 5;105(6):1168-1181. [Content Brief]
[2]. Patrick Lorès, et al. Mutations in TTC29, Encoding an Evolutionarily Conserved Axonemal Protein, Result in Asthenozoospermia and Male Infertility. Am J Hum Genet. 2019 Dec 5;105(6):1148-1167. [Content Brief]
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