Tripeptidyl-peptidase 1
Definition:
References:
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[1]. L Lin, et al. The human CLN2 protein/tripeptidyl-peptidase I is a serine protease that autoactivates at acidic pH. J Biol Chem. 2001 Jan 19;276(3):2249-55. [Content Brief]
[2]. Aritra Pal, et al. Structure of tripeptidyl-peptidase I provides insight into the molecular basis of late infantile neuronal ceroid lipofuscinosis. J Biol Chem. 2009 Feb 6;284(6):3976-84. [Content Brief]
[3]. Jayita Guhaniyogi, et al. Crystal structure and autoactivation pathway of the precursor form of human tripeptidyl-peptidase 1, the enzyme deficient in late infantile ceroid lipofuscinosis. J Biol Chem. 2009 Feb 6;284(6):3985-97. [Content Brief]