Ubiquitin-conjugating enzyme E2 Z

Definition:

Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.

References:

[1]. Jianping Jin, et al. Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging. Nature. 2007 Jun 28;447(7148):1135-8. [Content Brief]

[2]. Kyung Mi Park, et al. Identification of novel regulators of apoptosis using a high-throughput cell-based screen. Mol Cells. 2007 Apr 30;23(2):170-4. [Content Brief]

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