2. Anti-infection
  3. Fungal
  4. Bis(methylthio)gliotoxin

Bis(methylthio)gliotoxin  (Synonyms: Bisdethiobis(methylthio)gliotoxin; FR 49175; Dimethylgliotoxin)

Cat. No.: HY-N9710
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Bis(methylthio)gliotoxin is a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis.

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Bis(methylthio)gliotoxin

Bis(methylthio)gliotoxin Estructura química

No. CAS : 74149-38-5

Tamaño Precio Stock Cantidad
1 mg Obtener un presupuesto 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
5 mg   Obtener un presupuesto  
10 mg   Obtener un presupuesto  
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Bis(methylthio)gliotoxin Related Antibodies

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Descripciòn

Bis(methylthio)gliotoxin is a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis[1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
>2.81 μM
Compound: 3
Cytotoxicity against human HeLa cells
Cytotoxicity against human HeLa cells
[PMID: 20303767]
HUVEC IC50
1.12 μM
Compound: 3
Cytotoxicity against HUVEC
Cytotoxicity against HUVEC
[PMID: 20303767]
Jurkat IC50
140 μM
Compound: 3
Cytotoxicity against human Jurkat cells after 40 hrs bioluminescence assay
Cytotoxicity against human Jurkat cells after 40 hrs bioluminescence assay
[PMID: 20303767]
Macrophage ED50
>10 μM
Compound: 3
Immunomodulatory activity in macrophage assessed as inhibition of phagocytosis
Immunomodulatory activity in macrophage assessed as inhibition of phagocytosis
[PMID: 20303767]
P388 IC50
0.11 μM
Compound: 3
Cytotoxicity against mouse P388 cells after 96 hrs by MTT assay
Cytotoxicity against mouse P388 cells after 96 hrs by MTT assay
[PMID: 22148349]
PC-3 IC50
0.39 μM
Compound: 310
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 38181652]
U-937 IC50
0.2 μM
Compound: 310
Cytotoxicity against human U-937 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human U-937 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 38181652]
Peso molecular

356.46

Fòrmula

C15H20N2O4S2
No. CAS
SMILES

CS[C@]12N(C([C@@](SC)(N(C2=O)C)CO)=O)[C@@]3([H])C(C1)=CC=C[C@@H]3O
Structure Classification
Initial Source

genus Aspergillus
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Bis(methylthio)gliotoxin Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bis(methylthio)gliotoxin74149-38-5Bisdethiobis(methylthio)gliotoxin FR 49175 DimethylgliotoxinFR49175FR 49175FR-49175Fungalstablereliable markerinvasive aspergillosisgliotoxindiagnosisInhibitorinhibitorinhibit

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Nombre del producto:
Bis(methylthio)gliotoxin
Cat. No.:
HY-N9710
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