Triclosan-d3
Based on 1 Customer Validation
Triclosan-d3 is the deuterium labeled Triclosan. Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments.
For research use only. We do not sell to patients.
- Purity: 98.11%
- CAS No.: 1020719-98-5
- Formula: C12H4D3Cl3O2
- Molecular Weight:292.56
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1020719-98-5
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Unlabeled Cas 3380-34-5
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Appearance Solid
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Molecular Weight 292.56
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Formula C12H4D3Cl3O2
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Color White to off-white
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SMILES
OC1=CC(Cl)=CC=C1OC2=C(Cl)C([2H])=C(Cl)C([2H])=C2[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (341.81 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Weatherly LM, et al. Triclosan exposure, transformation, and human health effects. J Toxicol Environ Health B Crit Rev. 2017;20(8):447-469. [Content Brief]
[3]. Ley C, et al. Triclosan and triclocarban exposure and thyroid function during pregnancy-A randomized intervention. Reprod Toxicol. 2017 Dec;74:143-149. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4181 mL | 17.0905 mL | 34.1810 mL | 85.4526 mL |
| 5 mM | 0.6836 mL | 3.4181 mL | 6.8362 mL | 17.0905 mL | |
| 10 mM | 0.3418 mL | 1.7091 mL | 3.4181 mL | 8.5453 mL | |
| 15 mM | 0.2279 mL | 1.1394 mL | 2.2787 mL | 5.6968 mL | |
| 20 mM | 0.1709 mL | 0.8545 mL | 1.7091 mL | 4.2726 mL | |
| 25 mM | 0.1367 mL | 0.6836 mL | 1.3672 mL | 3.4181 mL | |
| 30 mM | 0.1139 mL | 0.5697 mL | 1.1394 mL | 2.8484 mL | |
| 40 mM | 0.0855 mL | 0.4273 mL | 0.8545 mL | 2.1363 mL | |
| 50 mM | 0.0684 mL | 0.3418 mL | 0.6836 mL | 1.7091 mL | |
| 60 mM | 0.0570 mL | 0.2848 mL | 0.5697 mL | 1.4242 mL | |
| 80 mM | 0.0427 mL | 0.2136 mL | 0.4273 mL | 1.0682 mL | |
| 100 mM | 0.0342 mL | 0.1709 mL | 0.3418 mL | 0.8545 mL |
Triclosan-d3 Related Classifications
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