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Cat. No.: HY-W1063360

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EZH2 ligand-5

EZH2 ligand-5 is an EZH2 ligand. EZH2 ligand-5 serves as a ligand for the target protein in the synthesis of PROTAC EZH2 degraders, such as MS177 (HY-148333). EZH2 ligand-5 can be used in leukemia research.

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CAS No.: 2225940-27-0
Formule: C₃₀H₃₈N₈O₂
Masse moléculaire:542.68

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Please store the product under the recommended conditions in the Certificate of Analysis.

EZH2 ligand-5 Chemical Structure

CAS No.: 2225940-27-0

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Fluorescent Dye

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
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Calculators
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Activité biologique

Description

IC₅₀ & Target^[1]

EZH2

Voir tous les produits spécifiques à Isoform Histone Methyltransferase :

Chemical Information

CAS No. 2225940-27-0
Masse moléculaire 542.68
Formule C₃₀H₃₈N₈O₂
SMILES

O=C(C1=CC(C2=CC=C(N3CCN(CCN)CC3)N=C2)=CC4=C1C=NN4C(C)C)NCC5=C(C)C=C(C)NC5=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Wang J, et al. EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis. Nat Cell Biol. 2022 Mar;24(3):384-399. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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EZH2 ligand-5

Voir tous les produits spécifiques à Isoform Histone Methyltransferase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

EZH2 ligand-5 Related Classifications

HY-W1063360 Related Classifications