CCIN - calicin Gene

Also Known as BTBD20; KBTBD14

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 881

About CCIN

Cytogenetic location: 9p13.3 Genomic coordinates (GRCh38): 9:36,169,388-36,171,334 (from NCBI)

This gene has 1 transcript (splice variant), 102 orthologues and 54 paralogues.

Summary

The protein encoded by this gene is a basic protein of the sperm head Cytoskeleton. This protein contains kelch repeats and a BTB/POZ domain and is necessary for normal morphology during sperm differentiation. This gene is intronless. [provided by RefSeq, Jul 2008]

CCIN Products (1)

mRNA Protein Name
NM_005893.3 NP_005884.2 calicin
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
Biological Process GO Annotation Evidence Références Source
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
36546111 GOA
Cellular Component GO Annotation Evidence Références Source
located in cytoskeletal calyx IDA
IDA: Inferred from direct assay
36546111 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCIN Protein Structure

BTB

BTB: BTB/POZ domain (18 - 127)

BACK

BACK: BTB And C-terminal Kelch (133 - 233)

Kelch_3

Kelch_3: Galactose oxidase, central domain (326 - 371)

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  • 588 a.a.
Protein Preferred Names Protein Names

calicin

  • testis tissue sperm-binding protein Li 65n

Related Diseases

Diseases Alias
Lateral Sinus Thrombosis
  • Thrombosis Of Lateral Venous Sinus

  • Thrombosis Transverse Sinus

Kluver-Bucy Syndrome
  • Bilateral Temporal Lobe Disorder

  • Klüver-Bucy Syndrome

  • Klver-Bucy Syndrome

  • Kluver Bucy Syndrome

  • Memory Loss, Extreme Sexual Behavior, Placidity, And Visual Distractibility

  • Post-Encephalitic Kluver Bucy Syndrome

  • Post-Traumatic Kluver Bucy Syndrome

Spermatogenic Failure 9
  • Male Infertility Due To Globozoospermia

  • SPGF9

  • Male Infertility Due To Round-Headed Spermatozoa

  • Globozoospermia, Complete

  • Globozoospermia, Total

  • Globozoospermia

  • Globozoospermia Syndrome

  • Round-Headed Sperm Syndrome

  • Globozoospermia Complete

  • Globozoospermia Total

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus CCIN MGD MGI:3045316
Macaca mulatta CCIN VGNC VGNC:70715
Rattus norvegicus CCIN RGD RGD:1359369
Canis familiaris CCIN VGNC VGNC:38878
Felis catus CCIN VGNC VGNC:60534
Bos taurus CCIN VGNC VGNC:26939
Others CCIN NCBI