100827-28-9
100827-28-9
Chemical Structure
Erbstatin
- CAS No.: 100827-28-9
- Formula:C9H9NO3
- Molecular Weight:179.17
IUPAC Name: (E)-N-(2,5-dihydroxystyryl)formamide
InChIKey: SIHZWGODIRRSRA-ONEGZZNKSA-N
SMILES: O=CN/C=C/C1=CC(O)=CC=C1O
Biological Activity: Erbstatin, a EGFR kinase inhibitor, possesses antineoplastic effect[1][2].
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Erbstatin | Erbstatin, a EGFR kinase inhibitor, possesses antineoplastic effect. | |||||||||||||||||||||
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References
- [1]. Shigeki Kobayashi, et al. Diastereomer-specific effects of double-stranded peptides conjugated with -L-Tyr-L-Phe- or -L-Tyr-D-Phe- residues on tyrosine phosphorylation and inhibition of src(ts)NRK, A431, MCF-7, and DU145 cell growth. Chem Pharm Bull (Tokyo). 2007 Nov;55(11):1585-92. [Content Brief]
- [2]. M Toi, et al. Antineoplastic effect of erbstatin on human mammary and esophageal tumors in athymic nude mice. Eur J Cancer. 1990;26(6):722-4. [Content Brief]
Keywords
