1056459-37-0
1056459-37-0
Chemical Structure
Prasugrel chloride impurity
- CAS No.: 1056459-37-0
- Formula:C20H21ClFNO3S
- Molecular Weight:409.90
IUPAC Name: 5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
InChIKey: QQRQUTSPQINSKG-UHFFFAOYSA-N
SMILES: O=C(CCCCl)C(N1CCC2=C(C=C(OC(C)=O)S2)C1)C3=CC=CC=C3F
Biological Activity: Prasugrel chloride impurity is a catp impurity of Prasugrel, exacted from patent US20130345428A1, line 0053. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1][2].
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Prasugrel chloride impurity | Prasugrel chloride impurity is a catp impurity of Prasugrel, exacted from patent US20130345428A1, line 0053. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation. | |||||||||||||||||||||
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References
- [1]. Hiroyuki Miyata, et al. Method for production of prasugrel hydrochloride having high purity. US20130345428A1.
- [2]. Sugidachi A, et al. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost. 2007 Jul;5(7):1545-51. [Content Brief]
Keywords
