1087243-14-8
1087243-14-8
Chemical Structure
GRL-0496
- CAS No.: 1087243-14-8
- Formula:C14H9ClN2O2
- Molecular Weight:272.69
IUPAC Name: 5-chloropyridin-3-yl 1H-indole-4-carboxylate
InChIKey: BOSZJNSICHFHMA-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC2=C1C=CN2)OC3=CC(Cl)=CN=C3
Biological Activity: GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GRL-0496 | 99.20% | GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM. | ||||||||||||||||||||
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References
Keywords
