1146195-72-3
Chemical Structure
Fluorescein-thiourea-PEG2-azide
- CAS No.: 1146195-72-3
- Formula:C27H25N5O7S
- Molecular Weight:563.58
IUPAC Name: 1-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-3-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)thiourea
InChIKey: ZLPFCAHUXVVHPW-UHFFFAOYSA-N
SMILES: S=C(NC1=CC2=C(C3(C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)OC2=O)C=C1)NCCOCCOCCN=[N+]=[N-]
Biological Activity: Fluorescein-thiourea-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Fluorescein-thiourea-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Fluorescein-thiourea-PEG2-azide | Fluorescein-thiourea-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Fluorescein-thiourea-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
