117211-03-7
Chemical Structure
Cefetecol
Synonym(s): GR69153
- CAS No.: 117211-03-7
- Formula:C20H17N5O9S2
- Molecular Weight:535.51
InChIKey: ILZCDOYRDFDUPN-XUQRFURESA-N
SMILES: O=C1N2[C@@](SCC=C2C(O)=O)([H])[C@@H]1NC(/C(C3=CSC(N)=N3)=N\O[C@@H](C4=CC(O)=C(C=C4)O)C(O)=O)=O
Biological Activity: Ceftezole (GR69153) is a broad-spectrum cephalosporin antibiotic and an α-glucosidase inhibitor. Ceftezole inhibits bacterial cell lysis by inhibiting cell wall synthesis and binding to penicillin-binding proteins (PBPs). Ceftezole exhibits in vivo anti-diabetic activity in diabetic mice. Ceftezole can be used in antibacterial and anti-diabetic research[1][2].
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Cefetecol | Ceftezole (GR69153) is a broad-spectrum cephalosporin antibiotic and an α-glucosidase inhibitor. Ceftezole inhibits bacterial cell lysis by inhibiting cell wall synthesis and binding to penicillin-binding proteins (PBPs). Ceftezole exhibits in vivo anti-diabetic activity in diabetic mice. Ceftezole can be used in antibacterial and anti-diabetic research. | |||||||||||||||||||||
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- [1]. Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20(3):379-83. [Content Brief]
- [2]. Noto T, et al. Ceftezole, a new cephalosporin C derivative I. In vitro and in vivo antimicrobial activity. J Antibiot (Tokyo). 1976 Oct;29(10):1058-70. [Content Brief]
Keywords
