117545-11-6
117545-11-6
Chemical Structure
Bimakalim
Synonym(s): EMD-52692; SR-44866
- CAS No.: 117545-11-6
- Formula:C17H14N2O2
- Molecular Weight:278.31
IUPAC Name: 2,2-dimethyl-4-(2-oxopyridin-1(2H)-yl)-2H-chromene-6-carbonitrile
InChIKey: JTVSKASWNROQQF-UHFFFAOYSA-N
SMILES: N#CC1=CC=C2C(C(N3C=CC=CC3=O)=CC(C)(C)O2)=C1
Biological Activity: Bimakalim (EMD-52692) is an ATP-sensitive potassium channel opener. Bimakalim reduces transmural MPO activity. Bimakalim mimics the effects of ischemic preconditioning to reduce infarct size, adenosine release, and neutrophil function in dogs[1].
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Bimakalim | Bimakalim (EMD-52692) is an ATP-sensitive potassium channel opener. Bimakalim reduces transmural MPO activity. Bimakalim mimics the effects of ischemic preconditioning to reduce infarct size, adenosine release, and neutrophil function in dogs. | |||||||||||||||||||||
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References
Keywords
