1186049-44-4
1186049-44-4
Chemical Structure
DDO-02005
- CAS No.: 1186049-44-4
- Formula:C21H27Cl2N3O2
- Molecular Weight:424.36
IUPAC Name: 1-(benzo[d]oxazol-2-ylmethyl)-N-(4-methoxybenzyl)piperidin-4-amine dihydrochloride
InChIKey: DVFKTQCMJJIJDS-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)CNC2CCN(CC3=NC4=CC=CC=C4O3)CC2.[H]Cl.[H]Cl
Biological Activity: DDO-02005 is a potent Kv1.5 potassium channel inhibitor with an IC50 value of 0.72 μM. DDO-02005 has good anti-atrial fibrillation (AF) effect in CaCl2-ACh AF rats model and effective anti-arrhythmic activity caused by aconitine[1].
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DDO-02005 | DDO-02005 is a potent Kv1.5 potassium channel inhibitor with an IC50 value of 0.72 μM. DDO-02005 has good anti-atrial fibrillation (AF) effect in CaCl2-ACh AF rats model and effective anti-arrhythmic activity caused by aconitine. | |||||||||||||||||||||
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References
Keywords
