1216403-88-1
1216403-88-1
Chemical Structure
Disulfiram-d20
- CAS No.: 1216403-88-1
- Formula:C10D20N2S4
- Molecular Weight:316.66
InChIKey: AUZONCFQVSMFAP-DEHFLJNXSA-N
SMILES: C([2H])([2H])([2H])C([2H])([2H])N(C([2H])([2H])C([2H])([2H])[2H])C(=S)SSC(=S)N(C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H]
Biological Activity: Disulfiram-d20 is deuterium labeled Disulfiram-d20.
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Disulfiram-d20 | Disulfiram-d20 is deuterium labeled Disulfiram-d20. | |||||||||||||||||||||
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Disulfiram (Standard) | 99.54% | Disulfiram (Standard) is the analytical standard of Disulfiram. This product is intended for research and analytical applications. Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram + Cu2+ increases intracellular ROS levels triggering apoptosis of ovarian cancer stem cells[1-6]. | ||||||||||||||||||||
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Disulfiram | 99.77% | Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram, a copper ion carrier, with Cu2+ increases intracellular ROS levels and induces cuproptosis. | ||||||||||||||||||||
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