1221591-26-9
Chemical Structure
AubipyOMe
- CAS No.: 1221591-26-9
- Formula:C12H12AuCl2F6N2O2P
- Molecular Weight:629.07
InChIKey: YZIUJXMVWVJCTJ-UHFFFAOYSA-L
SMILES: [F-][P+5]([F-])([F-])([F-])([F-])[F-].[Cl-][Au+3]1([N]2=CC=C(C=C2C3=[N]1C=CC(OC)=C3)OC)[Cl-]
Biological Activity: AubipyOMe serves as a potent inhibitor of tartrate-resistant acid phosphatase (TRAP/ACP5), a metalloenzyme found in activated osteoclasts and macrophages, demonstrating IC50 values of 1.3 μM for TRAP5a and 1.8 μM for TRAP5b, while effectively inhibiting TRAP activity in extracts from murine macrophages and human lung tissue.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AubipyOMe | 99.0% | AubipyOMe serves as a potent inhibitor of tartrate-resistant acid phosphatase (TRAP/ACP5), a metalloenzyme found in activated osteoclasts and macrophages, demonstrating IC50 values of 1.3 μM for TRAP5a and 1.8 μM for TRAP5b, while effectively inhibiting TRAP activity in extracts from murine macrophages and human lung tissue. | ||||||||||||||||||||
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Keywords