125546-04-5
125546-04-5
Chemical Structure
LY 233053
- CAS No.: 125546-04-5
- Formula:C8H13N5O2
- Molecular Weight:211.22
IUPAC Name: (2S,4R)-4-((1H-tetrazol-5-yl)methyl)piperidine-2-carboxylic acid
InChIKey: FAAVTENFCLADRE-RITPCOANSA-N
SMILES: OC([C@@H](NCC1)C[C@@H]1CC2=NN=NN2)=O
Biological Activity: LY 233053 is a potent and competitive NMDA-receptor antagonist with anticonvulsant and antiepileptic efficacy[1][2].
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LY 233053 | LY 233053 is a potent and competitive NMDA-receptor antagonist with anticonvulsant and antiepileptic efficacy. | |||||||||||||||||||||
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References
- [1]. 1.K K Borowicz, et al. Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice. Epilepsia. 1996 Jul;37(7):618-24. [Content Brief]
- [2]. K P Madden, et al. Efficacy of LY233053, a competitive glutamate antagonist, in experimental central nervous system ischemia. J Neurosurg. 1992 Jan;76(1):106-10. [Content Brief]
Keywords
