1258877-17-6
Chemical Structure
JPHM-2-167
- CAS No.: 1258877-17-6
- Formula:C30H28N6O2
- Molecular Weight:504.58
SMILES: O=C(N(C1=CC=C(C2=CC=CC=C2)C=C1)C(N3C4=NC=CC=N4)=O)C3(CC5)CCN5CC6=NC=CC=C6C
Biological Activity: JPHM-2-167 (Compound 11) is a selective PHD (prolyl hydroxylase domain enzyme) inhibitor. JPHM-2-167 inhibits PHD2, PHD3 with IC50s of 0.253 μM and 3.95 μM, respectively. JPHM-2-167 can be used for chronic kidney disease [1].
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JPHM-2-167 | JPHM-2-167 (Compound 11) is a selective PHD (prolyl hydroxylase domain enzyme) inhibitor. JPHM-2-167 inhibits PHD2, PHD3 with IC50s of 0.253 μM and 3.95 μM, respectively. JPHM-2-167 can be used for chronic kidney disease . | |||||||||||||||||||||
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Keywords