126869-04-3
126869-04-3
Chemical Structure
IGN-2098
- CAS No.: 126869-04-3
- Formula:C22H32Cl2N4O2
- Molecular Weight:455.42
InChIKey: NTLKFRQIRDDXCH-RDRKJGRWSA-N
SMILES: O=C1N=C(NC/C=C/COC2=CC=CC(CN3CCCCC3)=C2)NC(C)=C1C.Cl.Cl
Biological Activity: IGN-2098 is an orally active, competitive histamine H2 receptor antagonist with a pA2 value of 7.32. IGN-2098 inhibits basal and stimulated gastric acid secretion. IGN-2098 accelerates ulcer healing, suppresses ulcer edge elevation, and protects gastric and duodenal mucosa from damage. IGN-2098 can be used in research related to gastric ulcers[1][2].
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IGN-2098 | IGN-2098 is an orally active, competitive histamine H2 receptor antagonist with a pA2 value of 7.32. IGN-2098 inhibits basal and stimulated gastric acid secretion. IGN-2098 accelerates ulcer healing, suppresses ulcer edge elevation, and protects gastric and duodenal mucosa from damage. IGN-2098 can be used in research related to gastric ulcers. | |||||||||||||||||||||
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References
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[1]. Uchida M, et al. [Therapeutic effect of IGN-2098, a new antiulcer drug (H2-antagonist), in the ulcer diminishing period against acetic acid-induced gastric ulcer in rats]. Nihon Yakurigaku Zasshi. 1995 Mar;105(3):153-9. Japanese.
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[2]. Okabe S, et al. [Effects of IGN-2098, a new histamine H2-receptor antagonist, on gastric secretion and gastric and duodenal lesions induced in rats. Comparison with roxatidine]. Nihon Yakurigaku Zasshi. 1992 Mar;99(3):167-80. Japanese.
[Content Brief]
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