127408-31-5
127408-31-5
Chemical Structure
Y-26763
- CAS No.: 127408-31-5
- Formula:C14H16N2O4
- Molecular Weight:276.29
IUPAC Name: N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)-N-hydroxyacetamide
InChIKey: IWTCFIIOUXJOOV-OLZOCXBDSA-N
SMILES: CC(N([C@H]1[C@H](O)C(C)(C)OC2=CC=C(C#N)C=C12)O)=O
Biological Activity: Y-26763 is a K+ channel opener and active metabolite of Y-27152[1]. Y-26763 is an ATP-sensitive K+ (KATP) channel activator[2].
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Y-26763 | 99.7% | Y-26763 is a K+ channel opener and active metabolite of Y-27152. Y-26763 is an ATP-sensitive K+ (KATP) channel activator. | ||||||||||||||||||||
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References
- [1]. Itoh T, et al. Effects of a newly synthesized K+ channel opener, Y-26763, on noradrenaline-induced Ca2+ mobilization in smooth muscle of the rabbit mesenteric artery. Br J Pharmacol. 1994 Jan;111(1):165-72. [Content Brief]
- [2]. Tran QTN, et al. The identification of naturally occurring labdane diterpenoid calcaratarin D as a potential anti-inflammatory agent. Eur J Med Chem. 2019 Jul 15;174:33-44. [Content Brief]
Keywords
