1382979-64-7
1382979-64-7
Chemical Structure
PI3K-IN-38
- CAS No.: 1382979-64-7
- Formula:C20H24N6O2
- Molecular Weight:380.44
IUPAC Name: 4-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[4,3-e]purin-2-yl)aniline
InChIKey: ZXKUIDJEEORBPY-UHFFFAOYSA-N
SMILES: CC1(C)OCCN2C1=NC3=C(N4CCOCC4)N=C(C5=CC=C(N)C=C5)N=C23
Biological Activity: PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].
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PI3K-IN-38 | PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo. | |||||||||||||||||||||
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References
Keywords
