1425049-20-2
1425049-20-2
Chemical Structure
RB-005
- CAS No.: 1425049-20-2
- Formula:C21H35NO
- Molecular Weight:317.51
IUPAC Name: 1-(4-octylphenethyl)piperidin-4-ol
InChIKey: PXLXLCZHGHRZAO-UHFFFAOYSA-N
SMILES: CCCCCCCCC1=CC=C(CCN2CCC(O)CC2)C=C1
Biological Activity: RB-005 is a selective inhibitor of sphingosine kinase 1 (SK1) (IC50=3.6 µM), with weaker inhibition of another isoenzyme, SK2. The selective inhibition of RB-005 helps to distinguish the biological functions and roles of SK1 and SK2, which can be used in the study of inflammatory diseases and cancer[1].
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RB-005 | RB-005 is a selective inhibitor of sphingosine kinase 1 (SK1) (IC50=3.6 µM), with weaker inhibition of another isoenzyme, SK2. The selective inhibition of RB-005 helps to distinguish the biological functions and roles of SK1 and SK2, which can be used in the study of inflammatory diseases and cancer. | |||||||||||||||||||||
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References
Keywords
