1448429-06-8
1448429-06-8
Chemical Structure
Calpain Inhibitor-1
- CAS 番号: 1448429-06-8
- Formula:C19H17FN6O5S
- Molecular Weight:460.44
IUPAC Name: (2S,3S)-3-(((S)-1-(((1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl)methyl)amino)-1-oxo-3-(thiazol-4-yl)propan-2-yl)carbamoyl)oxirane-2-carboxylic acid
InChIKey: IPWMYOJQVHCYRC-JYJNAYRXSA-N
SMILES: FC(C=C1)=CC=C1N(N=N2)C=C2CNC([C@H](CC3=CSC=N3)NC([C@@H]4[C@H](O4)C(O)=O)=O)=O
Biological Activity: Calpain Inhibitor-1 (compound 36) is a potent and selective cysteine protease calpain 1 (Cal1) inhibitor (IC50=100 nM; Ki=2.89 μM)[1].
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Calpain Inhibitor-1 | Calpain Inhibitor-1 (compound 36) is a potent and selective cysteine protease calpain 1 (Cal1) inhibitor (IC50=100 nM; Ki=2.89 μM). | |||||||||||||||||||||
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References
Keywords
