149725-15-5
Chemical Structure
LY 806303
- CAS No.: 149725-15-5
- Formula:C16H14O5S
- Molecular Weight:318.34
IUPAC Name: methyl 3-(isobutyryloxy)benzo[4,5]thieno[3,2-b]furan-2-carboxylate
InChIKey: STCBJZIZCOASHY-UHFFFAOYSA-N
SMILES: O=C(OC)C1=C(C2=C(O1)C3=CC=CC=C3S2)OC(C(C)C)=O
Biological Activity: LY 806303 is a potent and selective inhibitor of human α-thrombin. LY 806303 specifically acylates Ser-205 within the catalytic triad of α-thrombin on the heavy chain and a key site involved in the enzymatic activity of thrombin. The mechanism of action of LY 806303 as an enzyme inhibitor is through the specific acylation of this catalytic serine residue[1].
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LY 806303 | LY 806303 is a potent and selective inhibitor of human α-thrombin. LY 806303 specifically acylates Ser-205 within the catalytic triad of α-thrombin on the heavy chain and a key site involved in the enzymatic activity of thrombin. The mechanism of action of LY 806303 as an enzyme inhibitor is through the specific acylation of this catalytic serine residue. | |||||||||||||||||||||
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Keywords
