1507362-00-6
Chemical Structure
TNKS 22
Synonym(s): TNKS-IN-22
- CAS No.: 1507362-00-6
- Formula:C25H25N5O3S
- Molecular Weight:475.56
IUPAC Name: 3-((4-oxo-1,4-dihydroquinazolin-2-yl)thio)-N-((1r,4r)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)cyclohexyl)propanamide
InChIKey: IOMJPRIMVDNEHH-IYARVYRRSA-N
SMILES: O=C1C2=CC=CC=C2NC(SCCC(N[C@@H]3CC[C@@H](C4=NN=C(C5=CC=CC=C5)O4)CC3)=O)=N1
Biological Activity: TNKS 22 (compound 22) is an orally active and selective tankyrase inhibitor. TNKS 22 inhibits TNKS1 and TNKS2 with IC50s of 0.1 and 4.1 nM, respectively[1].
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TNKS 22 | TNKS 22 (compound 22) is an orally active and selective tankyrase inhibitor. TNKS 22 inhibits TNKS1 and TNKS2 with IC50s of 0.1 and 4.1 nM, respectively. | |||||||||||||||||||||
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Keywords