153607-44-4
153607-44-4
Chemical Structure
S-14489
- CAS No.: 153607-44-4
- Formula:C22H26N2O2
- Molecular Weight:350.45
IUPAC Name: 1-(2-(bicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)ethyl)-4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazine
InChIKey: DHYRQVXQZAGWKI-UHFFFAOYSA-N
SMILES: C12=CC=CC(N3CCN(CCC4C5=C(C4)C=CC=C5)CC3)=C1OCCO2
Biological Activity: S-14489 is an orally active selective postsynaptic 5-HT1A receptor antagonist with a pKi of 9.2. S-14489 can act as a 5-HT1A autoreceptor agonist and inhibit striatal 5-hydroxytryptophan accumulation. S-14489 can be used for the research of neurological disease[1].
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S-14489 | S-14489 is an orally active selective postsynaptic 5-HT1A receptor antagonist with a pKi of 9.2. S-14489 can act as a 5-HT1A autoreceptor agonist and inhibit striatal 5-hydroxytryptophan accumulation. S-14489 can be used for the research of neurological disease. | |||||||||||||||||||||
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References
Keywords
