1581714-49-9
Chemical Structure
Atuzabrutinib
Synonym(s): SAR 444727; PRN473
- CAS No.: 1581714-49-9
- Formula:C30H30FN7O2
- Molecular Weight:539.60
IUPAC Name: (R,E)-2-(3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)-4,4-dimethylpent-2-enenitrile
InChIKey: KZMQPYCXSAGLTB-ZWUNQBBJSA-N
SMILES: NC1=C2C(N([C@H]3CN(CCC3)C(/C(C#N)=C/C(C)(C)C)=O)N=C2C4=C(C=C(C=C4)OC5=CC=CC=C5)F)=NC=N1
Biological Activity: Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Atuzabrutinib | 98.00% | Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling. | ||||||||||||||||||||
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Keywords
