1638885-61-6
1638885-61-6
Chemical Structure
Apalutamide-d3
Synonym(s): ARN-509-d3
- CAS No.: 1638885-61-6
- Formula:C21H12D3F4N5O2S
- Molecular Weight:480.45
IUPAC Name: 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(methyl-d3)benzamide
InChIKey: HJBWBFZLDZWPHF-FIBGUPNXSA-N
SMILES: O=C1C2(CCC2)N(C3=CC(F)=C(C=C3)C(NC([2H])([2H])[2H])=O)C(N1C4=CN=C(C#N)C(C(F)(F)F)=C4)=S
Biological Activity: Apalutamide-d3 is the deuterium labeled Apalutamide[1]. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[2].
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Apalutamide-d3 | Apalutamide-d3 is the deuterium labeled Apalutamide. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | |||||||||||||||||||||
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Apalutamide (Standard) | ≥98% | Apalutamide (Standard) is the analytical standard of Apalutamide. This product is intended for research and analytical applications. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | ||||||||||||||||||||
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Apalutamide-13C,d3 | 99.90% | Apalutamide-13C,d3 is the 13C- and deuterium labeled Apalutamide. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | ||||||||||||||||||||
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Apalutamide-d4 | 99.93% | Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | ||||||||||||||||||||
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Apalutamide-d7 | Apalutamide-d7 is deuterated labeled Apalutamide (HY-16060). Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | |||||||||||||||||||||
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Apalutamide | 99.94% | Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | ||||||||||||||||||||
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References
